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基於臨床指南自動核查處方禁忌與相互作用，保障用藥安全。
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Act as a senior clinical pharmacist and review the following prescription for compliance: The patient is a 65-year-old male with a history of chronic kidney disease (creatinine clearance 45ml/min) and hypertension. The current prescription includes Amoxicillin, Amlodipine, and Ibuprofen. Focus on analyzing drug-drug interactions, the necessity for dosage adjustments, and potential nephrotoxicity risks, providing recommendations aligned with clinical guidelines.
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請作為資深臨床藥師，對以下患者處方進行合規性審查：患者為65歲男性，既往有慢性腎功能不全（肌酐清除率45ml/min）和高血壓病史，當前處方包含阿莫西林、氨氯地平和布洛芬。請重點分析藥物間的相互作用、劑量調整必要性及潛在腎毒性風險，並給出符合臨床指南的用藥建議。
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