Automatically checks contraindications and interactions against clinical guidelines to ensure medication safety.
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Act as a senior clinical pharmacist and review the following prescription for compliance: The patient is a 65-year-old male with a history of chronic kidney disease (creatinine clearance 45ml/min) and hypertension. The current prescription includes Amoxicillin, Amlodipine, and Ibuprofen. Focus on analyzing drug-drug interactions, the necessity for dosage adjustments, and potential nephrotoxicity risks, providing recommendations aligned with clinical guidelines.
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