OpenAI's second-highest-ranking executive Fidji Simo is stepping down from her full-time role due to a neuroimmune disease recurrence, transitioning to a part-time consultant. She joined the board in 2024 and became CEO of the applications division in May 2025. Her departure comes as ChatGPT growth slows and OpenAI prepares for a potential IPO amid fierce competition with Anthropic, adding uncertainty to strategic execution.





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